Study of Computational Biotechnology (Bioinformatics) on Telang Flower Kombucha (Clitoria Terantea L) as an Immunomodulator to Suppress Immunoglobulin E (IgE) for Allergy Sufferers

نویسندگان

چکیده

Telang flower kombucha has been known to have pharmacological movement in vitro repressing the development of microbes and organisms. Besides that, it also potential vivo inhibit cholesterol livestock, so that can be used or utilized as an active ingredient drugs cosmetics. In addition, allergy cause immunity tend decrease due synthesis immunoglobulin E protein, this study aims provide initial picture for sufferers through computational biotechnology bioinformatics studies on vitexin compound tela formation IgE a based its binding affinity value. The research method was molecular docking validation butterfly pea inhibiting formation. results single point calculations geometric optimization were 2.99585 kcal/mol 5.20442 respectively. show value -7.1, contained telang is able Immunoglobulin (IgE) one causes allergies.

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ژورنال

عنوان ژورنال: Jurnal Biologi Tropis

سال: 2023

ISSN: ['1411-9587', '2549-7863']

DOI: https://doi.org/10.29303/jbt.v23i2.4895